Outlook 2007 and Outlook 2003 maintain a list of "allowed" address types in the registry. Outlook hands over messages that are addressed to an "allowed" address type to Exchange Server for further processing. When messages are addressed to an address type that is not included in the "allowed" list, Outlook does not reference Exchange Server but immediately returns an NDR message.
This list in the registry is refreshed every time that Outlook starts a MAPI session in cached mode. This list is stored in the 01026687 registry entry under the following registry subkey:
HKEY_CURRENT_USER\Software\Microsoft\Windows NT\CurrentVersion\Windows Messaging Subsystem\Profiles\<Outlook Profile>\13dbb0c8aa05101a9bb000aa002fc45a