When you attempt to start the Microsoft Exchange Server information store,
you may encounter the following error in the Event Log:
Event ID: 5000
Source: MSExchangeIS
Category: none
Type: Error
Unable to initialize the Microsoft Exchange Information Store service.
Error 4021.
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This occurs when the Microsoft Exchange Server service account does not
have the correct permissions on the site object.
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Permissions can be set at the Organization, Site, and Configuration levels.
This error will only be generated if you remove the permissions from the
Microsoft Exchange Service Account at the Site level.
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Start the Microsoft Exchange Administrator program, select the Site in
which the IS will not start, click Properties from the File menu, click the
Permissions tab, and give the Microsoft Exchange Service Account the
Service Account Admin. Role.
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