Be aware that the update in the Microsoft Download Center applies to the Microsoft Installer (.msi)-based edition of Office 2010. It doesn't apply to the Office 2010 Click-to-Run editions, such as Microsoft Office 365 Home. (Determining your Office version)
This security update resolves vulnerabilities in Microsoft Office that could allow remote code execution if a user opens a specially crafted Office file. To learn more about these vulnerabilities, see Microsoft Common Vulnerabilities and Exposures CVE-2018-0950.
Note To apply this security update, you must have the release version of Service Pack 2 for Office 2010 installed on the computer.